1H-Benzotriazole, 1-(Methylsulfonyl)-
1-(甲磺酰)-1H-苯并三唑
CAS: 37073-15-7
Molecular Formula: C7H7N3O2S
1H-Benzotriazole, 1-(Methylsulfonyl)- - Names and Identifiers
1H-Benzotriazole, 1-(Methylsulfonyl)- - Physico-chemical Properties
| Molecular Formula | C7H7N3O2S |
| Molar Mass | 197.21 |
| Melting Point | 108-112°C(lit.) |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Appearance | Solid |
| Color | White |
| Storage Condition | Sealed in dry,Room Temperature |
1H-Benzotriazole, 1-(Methylsulfonyl)- - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/39 - |
| WGK Germany | 3 |
1H-Benzotriazole, 1-(Methylsulfonyl)- - Introduction
1-(Methanesulfonyl)-1H-benzotriazole is an organic compound with the chemical formula C9H8N3O3S. It is a white crystalline solid, insoluble in water, but soluble in organic solvents such as ethanol and dimethyl sulfite.
1-(Methanesulfonyl)-1H-benzotriazole has antibacterial and antifungal activities, so it is widely used in the field of medicine. It can be used as a synthetic intermediate for antibiotics, antiparasitic and antitumor drugs. In addition, it can also be used in the manufacture of fungicides and herbicides in agriculture.
The method for preparing 1-(methylsulfonyl)-1H-benzotriazole can be achieved by reacting benzotriazole and methanesulfonyl chloride. The reaction is added methanesulfonyl chloride to the benzotriazole and carried out under appropriate conditions. After completion of the reaction, the target compound can be obtained by crystallization and filtration.
Regarding safety information, 1-(methylsulfonyl)-1H-benzotriazole requires attention to some safety measures during use and storage. It may produce toxic sulfur oxide gas when heated or in contact with strong oxidants. Therefore, the use of open flames and mixing with strong oxidants should be avoided during operation. In addition, the operation should be carried out in a well-ventilated area, avoiding inhalation or contact with skin and eyes. If necessary, wear appropriate protective equipment such as gloves, goggles and masks.
1-(Methanesulfonyl)-1H-benzotriazole has antibacterial and antifungal activities, so it is widely used in the field of medicine. It can be used as a synthetic intermediate for antibiotics, antiparasitic and antitumor drugs. In addition, it can also be used in the manufacture of fungicides and herbicides in agriculture.
The method for preparing 1-(methylsulfonyl)-1H-benzotriazole can be achieved by reacting benzotriazole and methanesulfonyl chloride. The reaction is added methanesulfonyl chloride to the benzotriazole and carried out under appropriate conditions. After completion of the reaction, the target compound can be obtained by crystallization and filtration.
Regarding safety information, 1-(methylsulfonyl)-1H-benzotriazole requires attention to some safety measures during use and storage. It may produce toxic sulfur oxide gas when heated or in contact with strong oxidants. Therefore, the use of open flames and mixing with strong oxidants should be avoided during operation. In addition, the operation should be carried out in a well-ventilated area, avoiding inhalation or contact with skin and eyes. If necessary, wear appropriate protective equipment such as gloves, goggles and masks.
Last Update：2024-04-09 20:52:54
